Capecitabine is used
Do NOT use capecitabine if:
- Treating certain types of breast, colon, or colorectal cancer in some patients. It may be used alone or with other medicines in some cases.
- Capecitabine is an antimetabolite. It works by interfering with the production of proteins necessary for cancer cell growth and reproduction.
- you are allergic to any ingredient in capecitabine or to 5-fluorouracil
- you have severe kidney problems or you have been told that you lack the enzyme dihydropyrimidine dehydrogenase (DPD)
Contact your doctor or health care provider right away if any of these apply to you.
Before using capecitabine:
Some medical conditions may interact with capecitabine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- If you are pregnant, planning to become pregnant, or are breast-feeding
- If you are taking any prescription (particularly blood thinners) or nonprescription medicine, herbal preparation, or dietary supplement (vitamin E, aspirin, ibuprofen, naproxen)
- If you have allergies to medicines, foods, or other substances
- If you have a history of heart, kidney, or liver problems; bone marrow problems; or pain, redness, swelling, tingling, or tenderness of the palms of the hands or soles of the feet (hand-and-foot syndrome)
- If you have nausea, vomiting, diarrhea, inflammation or sores in the mouth, or an infection
- If you are undergoing chemotherapy or radiation therapy, or if you take folic acid or vitamins that contain folic acid
Some MEDICINES MAY INTERACT with capecitabine. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Certain anticoagulants (eg, phenprocoumon, warfarin) because the risk of bleeding may be increased by capecitabine
- Leucovorin because the risk of severe intestinal problems, diarrhea, and dehydration may be increased
- Hydantoins (eg, phenytoin) because their side effects may be increased by capecitabine